Qinghai News Net•Damei Qinghai Client News (Reported by reporter Cui Yongtao) International cooperation project undertaken by the Northwest Plateau Institute of Biology, Chinese Academy of Sciences”TargetingAMPK to interfere with type 2 diabetes, the discovery and action mechanism of Qinghai-Tibet characteristic active substances” project, separated a series of unique chemical components from a variety of Qinghai-Tibet characteristic plant resources, A convenient and efficient compound separation and preparation technology system has been established, and a corresponding compound library has been established.

Through cooperation at home and abroad, a mouse model based on in vitro differentiation of mature adipocytes, isolated heart ischemia/reperfusion injury and type 2 diabetes was established, and the preparation of compounds to activate AMPK signals to improve glucose and lipid metabolism was systematically studied. , Protect the biological effects of myocardial ischemia/reperfusion injury, and obtain 4 lead compounds with excellent activity. The project has passed the expert acceptance organized by the Qinghai Provincial Science and Technology Department.

In recent years, the Provincial Department of Science and Technology has given full play to the international cooperation and exchange platform, taking the development of high-level cooperation, strengthening the construction of talent teams, introducing high-level teams, improving the level of scientific research, and promoting scientific research and innovation capabilities as its foothold and starting point. A number of high-level scientific research results have been formed, which has promoted the integration of the ability and quality of scientific researchers in our province with international standards, and provided strong scientific and technological support for accelerating the development and utilization of characteristic biological resources on the Qinghai-Tibet Plateau in our province.

Qinghai News Net•Damei Qinghai Client News (Reported by reporter Cui Yongtao) International cooperation project undertaken by the Northwest Plateau Institute of Biology, Chinese Academy of Sciences”TargetingAMPK to interfere with type 2 diabetes, the discovery and action mechanism of Qinghai-Tibet characteristic active substances” project, separated a series of unique chemical components from a variety of Qinghai-Tibet characteristic plant resources, A convenient and efficient compound separation and preparation technology system has been established, and a corresponding compound library has been established.

Through cooperation at home and abroad, a mouse model based on in vitro differentiation of mature adipocytes, isolated heart ischemia/reperfusion injury and type 2 diabetes was established, and the preparation of compounds to activate AMPK signals to improve glucose and lipid metabolism was systematically studied. , Protect the biological effects of myocardial ischemia/reperfusion injury, and obtain 4 lead compounds with excellent activity. The project has passed the expert acceptance organized by the Science and Technology Department of Qinghai Province.

In recent years, the Provincial Department of Science and Technology has given full play to the international cooperation and exchange platform, taking the development of high-level cooperation, strengthening the construction of talent teams, introducing high-level teams, improving the level of scientific research, and promoting scientific research and innovation capabilities as its foothold and starting point. A number of high-level scientific research results have been formed, which promotes the ability and quality of scientific research personnel in our province to be in line with international standards, and provides strong scientific and technological support for accelerating the development and utilization of characteristic biological resources on the Qinghai-Tibet Plateau in our province.